Emerging digital trends from artificial intelligence, augmented reality, and virtual reality to the Internet of Things, made ICT ecosystems more latency sensitive and broadband connection become an essential part of our lives. Consequently, data centres are being pushed to the edge where computing is globally distributed to be closer to the end users. A globally distributed computing paradigm comes with new challenges for cooling and efficiency. Moreover, European Commission recently set a goal of making ICT infrastructures climate-neutral by 2030 therefore data centres and cooling systems are challenged to be smarter to keep up with energy efficiency measures. Artificial-Intelligence-Augmented Cooling System for Small Data Centres, ECO-Qube Project, aims to develop a state-of-the-art holistic management system to enhance energy efficiency and cooling performance by orchestrating both hardware and software components in edge computing applications.